21st Annual Scientific Sessions:
Interorgan Crosstalk in Heart and Vascular Metabolism
St. Louis, MO, USA 8-11 September 2024
21st Annual Scientific Sessions:
Interorgan Crosstalk in Heart and Vascular Metabolism
St. Louis, MO, USA 8-11 September 2024
21st Annual Scientific Sessions:
Interorgan Crosstalk in Heart and Vascular Metabolism
St. Louis, MO, USA 8-11 September 2024
8:00-17:00 |
Registration [Hotel Lobby] |
8:30-12:00 |
Trip to the Gateway Arch National Park |
13:00 |
SHVM Board Meeting (for board members only) |
14:00-16:00 |
Trainee Workshop |
14:00-14:30 |
Craig Lygate (Glasgow, United Kingdom) |
14:30-16:00 |
Demonstration of small animal model imaging Jie Zheng, James Quirk, Yongjian Liu, Cornelius von Morze (Saint Louis, MO, USA) Small animal ultrasound and surgical techniques Attila Kovacs, Carla J. Weinheimer (Saint Louis, MO, USA) |
16:30-17:00 |
Break time |
Opening Session |
|
17:00-17:15 |
Welcome from Organisers and SHVM President |
17:15-18:00 |
Special Lecture – Lung-Heart Crosstalk Chairs: Linda R. Peterson (Saint Louis, MO, USA) and Zoltan P. Arany (Philadelphia, PA, USA) Andrew J. Murray (Cambridge, United Kingdom) |
18:00-22:00 |
Informal dinner reception [Poolside at Hotel] |
8:00-17:00 |
Registration [Hotel Lobby] |
6:30-7:30 |
Optional Run/Walk (~1-3 mi / ~1.6-5 km) – Shaw Park (near hotel) |
7:00-8:00 |
Breakfast |
Session 1 • Cardiovascular - Pancreas & Diabetes Connections Chairs: Camila Manrique-Acevedo (Columbia, MO, USA) and Gary D. Lopaschuk (Edmonton, Canada) |
|
8:00-9:00 |
Keynote Lecture Robert E. Gerszten (Boston, MA, USA) |
9:00-9:30 |
Yang Kevin Xiang (Davis, CA, USA) |
9:30-10:00 |
Kim Mellor (Auckland, New Zealand) |
10:00-10:30 |
Coffee break |
10:30-11:00 |
John R. Ussher (Edmonton, Canada) |
11:00-11:15 |
Short talk: Justin Berger (Philadelphia, PA, USA) |
11:15-11:30 |
Short talk: Sean Tatum (St. Louis, MO, USA) |
11:30-12:15 |
Early Career Investigator ‘speed-mentoring’
|
12:15-13:00 |
Special Lecture & Lunch Anne Carol Goldberg (St. Louis, MO, USA) |
Session 2 • Cardiovascular – Liver Connections Chairs: Renata O. Pereira (Iowa City, IA, USA) and Bellina Mushala (Pittsburgh, PA, USA) |
|
13:00-13:30 |
Jiandie Lin (Ann Arbor, MI, USA) |
13:30-13:45 |
Short talk: Mandy Chan (St. Louis, MO, USA) |
13:45-14:15 |
Konstantinos Drosatos (Cincinnati, OH, USA) |
14:15-14:45 |
Joel D. Schilling (St. Louis, MO, USA) |
14:45-15:00 |
Short talk: Nikole Byrne (Graz, Austria) |
Session 3 • The “William C. Stanley” Early Investigator Awards Chairs: Daniel P. Kelly (Philadelphia, PA, USA) and Rebecca Ritchie (Melbourne, Australia) |
|
15:00-15:15 |
Kylene Harold (Oklahoma City, OK, USA) |
15:15-15:30 |
Sumeet Khetarpal (Boston, MA, USA) |
15:30-15:45 |
Marcos Castro Guarda (Oxford, United Kingdom) |
15:45-16:00 |
Stephanie Kereliuk (Durham, NC, USA) |
16:00-17:45 |
Poster Session I / Exhibitions |
17:45-18:15 |
Travel time |
18:15-22:00 |
Formal Dinner – St. Louis Art Museum |
8:00-17:00 |
Registration [Hotel Lobby] |
7:00-8:00 |
Breakfast |
Session 4 • Cardiovascular – Cancer Connections Chairs: Heinrich Taegtmeyer (Houston, TX, USA) and Luc Bertrand (Brussels, Belgium) |
|
8:00-8:30 |
Tomas Neilan (Boston, MA, USA) |
8:30-9:00 |
Jason Dyck (Edmonton, Canada) |
9:00-9:30 |
Vlad G. Zaha (Dallas, TX, USA) |
9:30-9:45 |
Short talk: Gregory Ducker (Salt Lake City, UT, USA) |
9:45-10:00 |
Short talk: Matthieu Zolondek (Edmonton, Canada) |
10:00-12:00 |
Poster Session II / Exhibitions |
12:00-13:00 |
Special Lecture & Lunch Mark Huffman (St. Louis, MO, USA) |
Session 5 • Cardiovascular – Adipose Connections Chairs: Sharon Cresci (St. Louis, MO, USA) and Ira J. Goldberg (New York, NY, USA) |
|
13:00-13:30 |
Christopher T. Nguyen (Cleveland, OH, USA) |
13:30-14:00 |
Ippei Shimizu (Osaka, Japan) |
14:00-14:30 |
Saumya Das (Boston, MA, USA) |
14:30-15:00 |
Coffee break |
15:00-15:30 |
Kristin Stanford (Columbus, OH, USA) |
15:30-16:00 |
Clair Crewe (St. Louis, MO, USA) |
16:00-16:15 |
Short talk: Kae Won Cho (Cheonan, Republic of Korea) |
16:15-16:30 |
Short talk: Lauren Watson (Auckland, New Zealand) |
16:30-17:30 |
Break time |
17:30-18:00 |
Travel time |
18:00-22:00 |
Gala Dinner – Grant’s Farm |
7:00-8:00 |
Breakfast |
8:00-9:00 |
"William C. Stanley" Award Lecture Chairs: Lisa C. Heather (Oxford, United Kingdom) and Adam R. Wende (Birmingham, AL, USA) Martin E. Young (Birmingham, AL, USA) |
Session 6 • Cardiovascular – Brain Connections Chairs: Lisa C. Heather (Oxford, United Kingdom) and Adam R. Wende (Birmingham, AL, USA) |
|
9:00-9:30 |
Florin Despa (Lexington, KY, USA) |
9:30-10:00 |
Min-Seon Kim (Seoul, Republic of Korea) |
10:00-10:30 |
Olujimi Ajijola (Los Angeles, CA, USA) |
10:30-11:00 |
Coffee break |
Session 7 • Cardiovascular – GI/Immune Connections Chairs: Kory J. Lavine (St. Louis, MO, USA) and Hyoung Kyu Kim (Busan, Republic of Korea) |
|
11:00-11:30 |
Thomas A. Vallim (Los Angeles, CA, USA) |
11:30-12:00 |
Special Lecture Wilson Tang (Cleveland, OH, USA) |
12:00-12:30 |
Laurel Lee (Boston, MA, USA) |
12:30-12:45 |
Invitation to SHVM 2025 Bordeaux, France • Veronique Lacombe (Stillwater, OK, USA) |
12:45-13:00 |
Concluding Remarks Organizers and SHVM President |
13:00-14:00 |
Box Lunch and/or Depart |
Session 8 • SPECIAL SESSION Chairs: Jaetaek Kim (KSoLA, Republic of Korea) and Adam R. Wende (SHVM, USA) |
|
14:00-14:20 |
Nada A. Abumrad (St. Louis, MO, USA) |
14:20-14:40 |
Soon Jun Hong (Seoul, Republic of Korea) |
14:40-15:00 |
Hyun Kang (Seoul, Republic of Korea) |
15:00-15:30 |
Coffee break |
15:30-15:50 |
Sung Wan Chun (Asan, Republic of Korea) |
15:50-16:10 |
Samuel Klein (St. Louis, MO, USA) |
16:10-16:30 |
Arpita Vyas (St. Louis, MO, USA) |
16:30-17:00 |
Discussion and See You Next Year in Bordeaux! |
When preparing your poster, please remember that the available area on each poster board is 4 x 6 feet (1.2 x 1.8 m), height x width. Note that the orientation is landscape, not portrait. Prepare your poster accordingly, to whatever size you prefer, ensuring that it remains within the confines of the poster board.
Correct format... Wrong format...
Poster presenters are required to be available for discussion during their assigned session. The distribution of posters in the two sessions is indicated below.
P1.1 · Victoria Alvarado (Stony Brook, NY, U.S.A.)
Neutral sphingomyelinase-2 is required for doxorubicin-induced cardiotoxicity
P1.2 · Justin H. Berger (Philadelphia, PA, U.S.A.)
Whole body MondoA deletion protects against diet-induced obesity
P1.3 · Nikole J. Byrne (Graz, Austria)
Loss of SIRT5 accelerates the development of pressure-overload induced heart failure
P1.4 · Jordan S.F. Chan (Edmonton, Canada)
Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy
P1.5 · Mandy M. Chan (St. Louis, MO, U.S.A.)
Induction of TFEB promotes Kupffer cell survival and reduces liver pathology in metabolic dysfunction-associated steatotic liver disease (MASLD)
P1.6 · John C. Chatham (Birmingham, AL, U.S.A.)
Comparing the effects of glucose deprivation and 2-deoxyglucose on O-linked N-acetylglucosamine (O-GlcNAc) protein modification levels in cardiomyocytes
P1.7 · Ick-Mo Chung (Seoul, Republic of Korea)
Immobilization and electric shock inhibits arterial endothelial NO formation by CRH through activation of NLRP3 inflammasome and ER stress pathway
P1.8 · Rachel M. Crawford (Iowa City, IA, U.S.A.)
Norepinephrine stimulates uncoupled glutamate-supported respiration in cardiac mitochondria mediated by glutamic-oxaloacetic transaminase
P1.9 · Gregory S. Ducker (Salt Lake City, UT, U.S.A.)
Direct mitochondrial oxidation of circulating lactate by cardiac tissue is protective in models of heart failure
P1.10 · Zachary Foulks (St. Louis, MO, U.S.A.)
Unraveling the mechanism behind the ketogenic diet-mediated reversal of heart failure in mice
P1.11 · Krzysztof F. Galla (Warszawa, Poland)
Effects of progesterone and mifepristone on LDL-C and other lipids serum levels in female rats
P1.12 · Stefan Gross (Greifswald, Germany)
Greater visceral fat attenuates inflammation-reducing effects of higher cardiorespiratory fitness: Results from the population-based Study of Health in Pomerania (SHIP-START-2 / SHIP-TREND-0), Germany
P1.13 · Jin Han (Busan, Republic of Korea)
Cereblon-induced endoplasmic reticulum stress in diabetic cardiomyopathy
P1.14 · Gyu Seong Heo (St. Louis, MO, U.S.A.)
PET imaging of macrophage subset dynamics in atherosclerosis
P1.15 · Sam M. Hogue (St. Louis, MO, U.S.A.)
The effects of age and temperature acclimation on ROS production and mitochondrial respiration in western painted turtles (Chrysemys picta bellii)
P1.16 · Jijun Huang (Los Angeles, CA, U.S.A.)
Deciphering transcriptome and cell-cell communication signature in heart failure with preserved ejection fraction at single cell resolution
P1.17 · Amanda D. Ifft (Cleveland, OH, U.S.A.)
Obesity-driven cardiometabolic regulation: effects on systemic metabolism and interorgan crosstalk in males
P1.18 · Sumeet Khetarpal (Boston, MA, U.S.A.)
Cardiac adaptation to endurance exercise training requires suppression of GDF15 via PGC-1α
P1.19 · Joanna Konieczny (Tromsø, Norway)
Investigating liver-heart crosstalk during fructose-induced liver steatosis
P1.20 · Tessa M. Lochetto (St. Louis, MO, U.S.A.)
PPTC7 maintains cardiac homeostasis by suppressing excessive mitophagy
P1.21 · Max Merilovich (Halifax, Canada)
Secretion associated ras-related GTPase-1B (Sar1b): A novel regulator of muscle branched-chain ketoacid content, insulin signaling, and mitochondrial function
P1.22 · Bellina Mushala (Pittsburgh, PA, U.S.A.)
Fatty acid dysregulation drives cardio-hepatic crosstalk in heart failure with preserved ejection fraction (HFpEF)
P1.23 · Akiyuki Nishimura (Okazaki, Aichi, Japan)
Supersulfide has critical roles in mitochondrial quality and ischemic resistance of the heart
P1.24 · Melanie Paillard (Bron, France)
Human and mouse demonstration of the sarcoplasmic reticulum-mitochondria Ca2+ coupling as a new therapeutic target in diabetic cardiomyopathy
P1.25 · Terri Pietka (St. Louis, MO, U.S.A.)
Lipoprotein Lipase transport occurs by small extracellular vesicles and is regulated by membrane neutral sphingomyelinase-2
P1.26 · Kerstin Preuss (Birmingham, AL, U.S.A.)
The influence of pyruvate dehydrogenase activation on acetylation and its impact on adaption to exercise-induced cardiac hypertrophy
P1.27 · Zana M. Ross (Pittsburgh, PA, U.S.A.)
CREBRF regulates cardiomyocyte function and stress response
P1.28 · Simon Sedej (Graz, Austria)
Therapeutic potential of atglistatin in heart failure with preserved ejection fraction
P1.29 · Ayushi Sood (Iowa City, IA, U.S.A.)
Brown adipose tissue-derived GDF15 promotes survival during myocardial infarction
P1.30 · Seyed Amirhossein Tabatabaei Dakhili (Edmonton, Canada)
Chemical development of a new class of succinyl CoA:3-ketoacid CoA transferase (SCOT) inhibitors with reduced brain permeability that promote glucose-lowering in obesity
P1.31 · Sean M. Tatum (St. Louis, MO, U.S.A.)
Cardiomyocyte derived ceramides drive diastolic heart failure
P1.32 · Kensuke Tsushima (Los Angeles, CA, U.S.A.)
Spatiotemporal phosphoinositide-AKT signaling regulates myocardial T-tubules and membrane dynamics
P1.33 · Rachel Weiss (St. Louis, MO, U.S.A.)
Loss of mitochondrial pyruvate transport initiates cardiac glycogen accumulation and heart failure
P1.34 · Seon Bu Yang (Seoul, Republic of Korea)
Ubxn4 deficiency aggravates hepatic steatosis in high-fat diet-fed mice
P1.35 · Jianhua Zhang (Birmingham, AL, U.S.A.)
Regulation of mitophagy in the heart and brain
P1.36 · Yuan Zhang (Los Angeles, CA, U.S.A.)
Increased catabolism of 2-hydroxyglutarate mitigates cardiac remodeling
P1.37 · Tanin Shafaati (Edmonton, Canada)
Increasing circulating ketones has minimal impact on the cardiac abnormalities present in a mouse model of Barth syndrome
P2.1 · James R. Bell (Bundoora, Australia)
Proteomic comparison of ovine epicardial and paracardial adipose tissue secretomes suggests paracardial adipose capacity to modulate atrial structure and function
P2.2 · Hugues Boel (Montreal, Canada)
Metabolic transcriptional and lipidomic benefits of EZH2 inhibition in the heart: which place for macrophages?
P2.3 · Marcos Castro Guarda (Oxford, United Kingdom)
Exploring the dual role of fumarate as an intracellular and extracellular hypoxia-induced signaling molecule
P2.4 · Jordan S.F. Chan (Edmonton, Canada)
High fructose-mediated prediabetes does not induce left ventricular diastolic dysfunction in male mice
P2.5 · Samuel F. Chang (Birmingham, AL, U.S.A.)
Previously increased cardiac protein O-GlcNAcylation enhances susceptibility to cardiac dysfunction in a response to pressure-overload through immune-cardiac crosstalk
P2.6 · Emeli Chatterjee (Boston, MA, U.S.A.)
Big things come in small packages: liver extracellular vesicles targeting the heart during MASLD
P2.7 · Christopher J. Clarke (Stony Brook, NY, U.S.A.)
Plasma and serum sphingolipids as biomarkers of doxorubicin-induced cardiotoxicity
P2.8 · Kaitlyn M.J.H. Dennis (Oxford, United Kingdom)
Sarcolemmal CD36 content is decreased in human heart failure patients, and is correlated with left ventricular ejection fraction
P2.9 · Anna A. Faakye (Oklahoma City, OK, U.S.A.)
The potential role of aspirin in modulating cardiac metabolism in a SIRT3 dependent manner
P2.10 · Christina Fu (St. Louis, MO, U.S.A.)
Untangling the cellular and molecular mechanisms of cardiogenic liver disease
P2.11 · Keshav Gopal (Edmonton, Canada)
Ovarian hormones mask cardiac dysfunction in an experimental model of type 2 diabetes
P2.12 · Chea-Myeong J. Ha (Birmingham, AL, U.S.A.)
Evaluating the impact of pyruvate dehydrogenase kinase (PDK) isozymes on diabetic cardiomyopathy in a type 2 diabetes mouse model
P2.13 · Kylene M. Harold (Oklahoma City, OK, U.S.A.)
Impacts of PFKFB2-mediated glycolytic regulation on cardiac function and electrophysiology
P2.14 · Estelle Heyne (Jena, Germany)
Hyperbaric oxygen treatment reveals spatiotemporal OXPHOS plasticity in the porcine heart
P2.15 · Lorenz M.W. Holzner (Cambridge, United Kingdom)
Hepatocyte-specific HIF2α deletion is associated with myocardial accumulation of lipotoxic lipids, and systolic and diastolic dysfunction in MASLD
P2.16 · Amanda D. Ifft (Cleveland, OH, U.S.A.)
Exposing female-specific cardiac mediated crosstalk with brown adipose tissue in metabolic syndrome
P2.17 · Stephanie Kereliuk (Durham, NC, U.S.A.)
GRK2-mediated cardiomyocyte signaling factors are responsible for heart-fat communication
P2.18 · Hyoung Kyu Kim (Busan, Republic of Korea)
Evogliptin, a DPP-4 inhibitor, prevents cardiac lipotoxicity and mitochondrial dysfunctions in type 2 diabetic mice model
P2.19 · Véronique A. Lacombe (Stillwater, OK, U.S.A.)
SARS-COV-2 Infection induces alterations of glucose metabolism in the cardiorespiratory system: Insights on virus-host crosstalk in a feline model
P2.20 · Thiago N. Menezes (St. Louis, MO, U.S.A.)
Liver PPTC7 knockout induces mitochondrial dysfunction in mice
P2.21 · Abigail Mulligan (Baltimore, MD, U.S.A.)
Metabolism of exogenous acyl-carnitines by cardiomyocytes
P2.22 · Fawaz T. Naeem (Philadelphia, PA, U.S.A.)
Targeted quantitative plasma metabolomics identifies metabolite signatures that distinguish heart failure with reduced and preserved ejection fraction
P2.23 · Jaume R. Otaegui Rabanal (St. Louis, MO, U.S.A.)
Molecular imaging of immune checkpoint inhibitors aggregated inflammatory response in atherosclerosis
P2.24 · Mark E. Pepin (Menlo Park, CA, U.S.A.)
Disrupting NNT prevents cardiometabolic heart failure with preserved ejection
P2.25 · Noemi Polgar (Honolulu, HI, U.S.A.)
The exocyst trafficking complex mediates fuel transporter membrane delivery and subsequent fuel uptake in cardiomyocytes
P2.26 · Julie H. Rennison (Cleveland, OH, U.S.A.)
Decreased expression of proteins that modulate mitochondrial structure precedes onset of atrial fibrillation in a mouse model of spontaneous atrial fibrillation
P2.27 · Mya A. Schmidt (Sturgeon County, Canada)
Sex differences in the murine response to lipopolysaccharides: are endogenous ketones responsible?
P2.28 · Georgios Siokatas (Cincinnati, OH, U.S.A.)
Cardiomyocyte KLF5 suppresses the abundance of the entire miR-30 cardioprotective family in ischemic cardiomyopathy through the circular-RNA circPRDM5
P2.29 · Nikola Srnic (Oxford, United Kingdom)
A high fat diet enriched with saturated compared to polyunsaturated fat has a more detrimental effect on the hepato-cardiac axis in healthy humans
P2.30 · Warren Tai (Los Angeles, CA, U.S.A.)
Cardiac-specific deletion of mitochondrial citrate carrier SLC25A1 does not impair cardiac function under normal or hemodynamic stress conditions
P2.31 · Benjamin D. Thackray (Cambridge, United Kingdom)
Maternal obesity alters cardiac mitochondria and substrate metabolism in young adult mouse offspring
P2.32 · Joseph R. Visker (Salt Lake City, UT, U.S.A.)
Enhancing mitochondrial pyruvate metabolism ameliorates myocardial ischemic reperfusion injury
P2.33 · Seon Bu Yang (Seoul, Republic of Korea)
RUNX3 negatively regulates agonists induced cardiac fibroblasts differentiation
P2.34 · Joo Mi Yi (Busan, Republic of Korea)
Epigenetic indicators of cardiovascular disease risk from low-dose ionizing radiation
P2.35 · Quanjiang Zhang (Los Angeles, CA, U.S.A.)
NNMT induction causes heart failure attributable to inducible ULK1 loss in cardiomyocytes
P2.36 · Matthieu C.P. Zolondek (Edmonton, Canada)
Cardiac-specific ROMO1 overexpression prevents loss of mitochondrial structure and function in a murine model of heart failure